Is GIFT a better fertility treatment?
Not
necessarily. GIFT stands for gamete intrafallopian transfer.
It involves the placement of ripe eggs directly into the fallopian
tube, along with a washed, processed sample of the husband's
sperm. It should be noted that the eggs are retrieved by the
vaginal ultrasound route just as in routine IVF. However,
the egg and sperm are placed into the fallopian tube using
Laparoscopy. Thus it is a more complicated surgical procedure
than routine IVF.
Patients with GIFT generally experience 5-10% higher pregnancy
rates; however, this increased pregnancy rate may be due to
patient selection, resulting in a group of patients with a
higher chance of successful pregnancy. Since fertilization
cannot be observed in GIFT, it is generally avoided where
male factor infertility is suspected. In addition, the fallopian
tubes have to be normal to undergo the GIFT procedure, or
else tubal pregnancies or failure to achieve pregnancy will
ensue. It should be noted that there are experimental methods
to perform GIFT through the vagina and cervix by using preformed
catheters or ultrasound guidance. These methods have not yet
proven to be as successful as routine GIFT, and for this reason
they are not routinely advised.
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